Bacitracin (Baneocin Powder) is a polypeptide antibiotic which inhibits bacterial cell wallsynthesis. It is especially active against gram-positive (Streptococcus spp./including beta hemolytic streptococcus/, Staphylococcus spp.) and some gram-negative microorganisms.Resistance to bacitracin is rare.
Neomycin is an aminoglycoside antibiotic that inhibits bacterial protein synthesis. It is active against gram-positive and gram-negative bacteria.
By using a combination of the two antibiotics, a wide spectrum of action of the drug andsynergistic effects against a number of microorganisms, such as staphylococci, are achieved.
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